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Research We Fund: Extramural Discovery Science
Detecting cancer early saves lives. Unfortunately, the important benefits of cancer screening are not reaching enough people. The purpose of this RFA is to fund innovative research that will facilitate more widespread cancer screening and early detection culminating in reduced cancer mortality.
Screening has proven to be one of the most impactful cancer-control strategies, yet many Americans are not reaping the benefits. Despite the United States being a high-resource country, the uptake, equity, and effectiveness of cancer screening are suboptimal, and socioeconomic inequalities in usage are widening. Additional research is necessary to test creative solutions for tackling this persistent problem and disturbing trend.
Applications Open in proposalCENTRAL: Jan. 2023
Application Due Date (all grant mechanisms): April 3, 2023
Application Review: June 2023
Award Notification: Oct. 2023
Grant Activation: Jan. 2024
Funds Available for Awards: $10 million for the 3 mechanisms
Program Contact: Kim Clarke at email@example.com
Cancer screening and early detection needs extend beyond improving the implementation of existing tests. There are proven screening tools for only 4 of the 20 most common cancer types in the US. It is paramount to identify through research effective strategies for detecting more cancer types early, while being mindful that technologies that are less expensive and less complex will enable their widest application.
This RFA, focused on testing innovative solutions to improve cancer screening and early detection, could entail better implementing existing screening tests, adapting current tests and technologies, or developing new tools.
We highly encourage creative approaches that will lead to more equitable, accessible, and holistic cancer screening and early detection (e.g., bundling evidence-based screening tests, integrating cancer prevention tactics into screening models, or developing technologies that could bring cancer screening to individuals rather than having people go to health care facilities).
Examples of possible research areas:
This Screening Priority Area RFA offers funding opportunities for investigators with a terminal degree at all career ranks.
All applications must be submitted by a college, university, medical school, or other eligible not-for-profit research organization within the United States, its territories, or the Commonwealth of Puerto Rico.
After Spring 2023, new or resubmitted applications will only be accepted for this RFA deadline on a limited basis.
Overview: Funds team science to advance cancer screening and early detection. All Team Award applications must clearly articulate how the team will synergize to accelerate scientific advancement and clinical benefit.
We define an interdisciplinary team as one having a well-justified representation of diverse research skills and perspectives, not merely team members representing different departments.
The team must consist of at least 3 members: Lead PI and at least 1 Team Principal and 1 Team Investigator.
Grant Term and Budget: The award is for a 5-year term with $1.2M total costs ($200K a year, plus 20% allowable indirect costs).
Letter-of-Intent (LOI) Requirements and Due Date: Resubmitted Team Award applications do not need to submit an LOI again. Any changes to the Team must be approved by the Scientific Director of the program. The proposal may not change more than 50% from the initial submission.
Invitation to Apply Date: By June 20, 2022, invitation-to-apply decisions will be communicated to applicants via proposalCENTRAL.
If the LOI is accepted, the application materials will become available in the PI’s proposalCENTRAL account.
Overview: Funds an independent research project that advances cancer screening and early detection.
Eligibility: You ARE eligible to submit a proposal if you:
Note: PI eligibility for this RFA is extended beyond the ACS standard career launching RSG. Active ACS grantees who meet the eligibility criteria can apply as long as the proposed project has no scientific overlap with currently funded projects.
Grant Term and Budget: Awards are for up to 4 years at $165K a year direct costs, plus 20% allowable indirect costs.
Note: Unlike our traditional RSG, we are not offering an expanded award term and budget for large, multilevel projects on screening health equity. If the research team is interdisciplinary (defined above), the Team Award could be an option for projects requiring more time and/or a larger budget.
Overview: Provides protected time (minimum of 50%) for junior faculty to be mentored and participate in cancer screening and early detection research training to aid their development as independent clinician scientists.
Eligibility: You ARE eligible to submit a proposal if you:
Grant Term and Budget: Award is for 3 to 5 years with $135K direct costs a year, plus 8% allowable indirect costs.
See the Clinician Scientist Development grant for more details.
Priority Area RFA in Screening Application Instructions and Policies
Goes to proposalCENTRAL