Key Statistics for Endometrial Cancer

In the United States, cancer of the endometrium (the lining of the uterus) is the most common cancer of the female reproductive organs.

How common is endometrial cancer?

The American Cancer Society estimates for endometrial cancer in the United States for 2026 are:

• About 68,270 new cases of endometrial cancer will be diagnosed.
• About 14,450 women will die from endometrial cancers.

These estimates include both endometrial cancers and uterine sarcomas. Up to 10% of endometrial cancers are sarcomas, so the actual numbers for endometrial cancer cases and deaths are slightly lower than these estimates.

Who gets endometrial cancer?

Endometrial cancer is the fourth most common cancer for women in the United States.

About 68% of uterine cancers are diagnosed when the cancer is in an early stage. This is largely because abnormal vaginal bleeding is an early symptom, particularly when it occurs after menopause. Anyone with vaginal bleeding after menopause should tell their doctor.

Endometrial cancer affects mainly post-menopausal women. The average age of women diagnosed with endometrial cancer is 60. It's uncommon in women under the age of 45.

Incidence trends

Overall incidence of endometrial cancer has stabilized overall and in White women in recent years. However, rates in women of all other racial and ethnic groups has continued to increase by 1.8% to 2.6% per year from 2013 to 2022.

Mortality trends

Endometrial cancer is one of the few cancers with increasing mortality; from 2014 to 2023 the death rate rose by 1.6% per year.

The endometrial cancer death rate in Black women is nearly double that in White women (9.0 versus 4.6 deaths per 100,000, respectively), likely due to unequal access to high-quality treatment.

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.