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At our National Cancer Information Center trained Cancer Information Specialists can answer questions 24 hours a day, every day of the year to empower you with accurate, up-to-date information to help you make educated health decisions. We connect patients, caregivers, and family members with valuable services and resources.
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For medical questions, we encourage you to review our information with your doctor.
For many people with colorectal cancer, treatment can remove or destroy the cancer. The end of treatment can be both stressful and exciting. You may be relieved to finish treatment, but find it hard not to worry about cancer coming back. This is very common if you’ve had cancer.
For other people, colorectal cancer may never go away completely. Some people may get regular treatment with chemotherapy, radiation therapy, or other treatments to try to control the cancer for as long as possible. Learning to live with cancer that does not go away can be difficult and very stressful.
Talk with your doctor about developing a survivorship care plan for you. This plan might include:
If you have completed treatment, you will likely have follow-up visits with your doctor for many years. It’s very important to go to all of your follow-up appointments. During these visits, your doctors will ask if you are having any problems and may do exams and lab tests or imaging tests to look for signs of cancer returning, a new cancer, or treatment side effects.
To some extent, the frequency of follow up visits and tests will depend on the stage of your cancer and the chance of it coming back.
Almost any cancer treatment can have side effects. Some might last for a few days or weeks, but others might last a long time. Some side effects might not even show up until years after you have finished treatment. Your doctor visits are a good time to ask questions and talk about any changes or problems you notice or concerns you have.
If there are no signs of cancer remaining, many doctors will recommend you have a physical exam and some of the tests listed below every 3 to 6 months for the first couple of years after treatment, then every 6 months or so for the next few years. People who were treated for early-stage cancers may do this less often.
In most cases, your doctor will recommend you have a colonoscopy about a year after surgery. If the results are normal, most people won’t need another one for 3 years. If the results of that exam are normal, then future exams often can be about every 5 years. If the colonoscopy shows abnormal areas or polyps, the test may be needed more often.
If you had rectal cancer that was removed with a transanal excision (the surgery was done through your anus), your doctor will likely recommend you have a proctoscopy every 3 to 6 months for the first couple of years after treatment, then every 6 months or so for the next few years. This allows the doctor to get a close look at the area where the tumor was to see if the cancer might be coming back.
Whether or not your doctor recommends imaging tests will depend on the stage of your cancer and other factors. CT scans may be done regularly, such as once every 6 months to a year, for those at higher risk of recurrence, especially in the first few years after treatment. People who had tumors in the liver or lungs removed might be scanned every 3 to 6 months for the first few years.
Carcinoembryonic antigen (CEA) is a substance called a tumor marker that can be found in the blood of some people with colorectal cancer. Doctors check levels of this marker with a blood test before treatment begins.
If it's high at first and then goes down to normal after surgery, it can be checked again when you come in for follow-up (typically every 3 to 6 months for the first couple of years after treatment, then every 6 months or so for the next few years). If the CEA level goes up again, it might be a sign that the cancer has come back, and colonoscopy or imaging tests might be done to try to find the site of recurrence.
If tumor marker levels weren’t elevated when the cancer was first found, they aren’t likely to be helpful as a sign of the cancer coming back.
Even after treatment, it’s very important to keep health insurance. Tests and doctor visits cost a lot, and even though no one wants to think of their cancer coming back, this could happen.
At some point after your cancer treatment, you might find yourself seeing a new doctor who doesn’t know about your medical history. It’s important to keep copies of your medical records to give your new doctor the details of your diagnosis and treatment.
Most side effects go away after treatment ends, but some may continue and need special care to manage. For example, if you have a colostomy or ileostomy, you may worry about doing everyday activities. Whether your ostomy is temporary or permanent, a health care professional trained to help people with colostomies and ileostomies (called an enterostomal therapist) can teach you how to care for it. Learn more about managing and caring for an ostomy in Colostomy Guide and Ileostomy Guide.
Some people with colon or rectal cancer may have long lasting trouble with chronic diarrhea, going to the bathroom frequently, or not being able to hold their stool. Some may also have problems with numbness or tingling in their fingers and toes (peripheral neuropathy) from chemo they received.
If you have (or have had) colorectal cancer, you probably want to know if there are things you can do (aside from your treatment) that can help lower your risk of the cancer growing or coming back, such as getting or staying active, eating a certain type of diet, or taking nutritional supplements. Fortunately, research has shown there are some things you can do that might be helpful.
Being overweight or obese (very overweight) is known to increase the risk of getting colorectal cancer. However, it’s not clear if having extra body weight raises the risk of colorectal cancer coming back or of dying from colorectal cancer. It's also not clear if losing weight during or after treatment can actually lower the risk of colorectal cancer recurrence.
Of course, getting to a healthy weight can have many other health benefits. But if you’re thinking about losing weight, it’s important to discuss this with your doctor, especially if you're still getting treatment or have just finished it.
A good deal of research suggests that people who get regular physical activity after treatment have a lower risk of colorectal cancer recurrence and a lower risk of dying from colorectal cancer. Physical activity has also been linked to improvements in quality of life, physical functioning, and fewer fatigue symptoms. It’s not clear exactly how much activity might be needed, but more seems to be better.
Some studies have also found that spending less time sitting or lying down is linked to a lower risk of dying from colorectal cancer.
It’s important to talk with your treatment team before starting a new physical activity program. This might include meeting with a physical therapist, too. Your team can help you plan a program that can be both safe and effective for you.
In general, it’s not clear that eating any specific type of diet can help lower your risk of colorectal cancer coming back. Some studies have suggested that colorectal cancer survivors who eat diets high in vegetables, fruits, whole grains, chicken, and fish might live longer than those who eat diets with more refined sugars, fats, and red or processed meats. But it’s not clear if this is due to effects on colorectal cancer or possibly to other health benefits of eating a healthy diet.
Still, there are clearly health benefits to eating well. For example, diets that are rich in plant sources are often an important part of getting to and staying at a healthy weight. Eating a healthy diet can also help lower your risk for some other health problems, such as heart disease and diabetes.
So far, no dietary supplements have been shown to clearly help lower the risk of colorectal cancer progressing or coming back. This doesn’t mean that none will help, but it’s important to know that none have been proven to do so.
Vitamin D: Some research has suggested that colorectal cancer survivors with higher levels of vitamin D in their blood might have better outcomes than those with lower levels. Other research has suggested that people with colorectal cancer who have low vitamin D levels may have a worse survival than those with normal levels, but more studies are needed. But it’s not yet clear if taking vitamin D supplements can affect outcomes.
Calcium: Some research has suggested that calcium supplements can lower the risk of colorectal polyps in people who have previously had polyps. Other research has suggested that people with early-stage colorectal cancer who take in a higher level of milk and calcium may have a lower the risk of dying. But it’s not clear if calcium supplements can lower the risk of colorectal cancer coming back.
Dietary supplements are not regulated like medicines in the United States – they do not have to be proven to work (or even be safe) before being sold, although there are limits on what they’re allowed to claim they can do. If you're thinking about taking any type of nutritional supplement, talk to your health care team first. They can help you decide which ones you can use safely while avoiding those that could be harmful.
Many studies have found that people who regularly take aspirin have a lower risk of colorectal cancer and polyps. Some evidence suggests that starting aspirin after someone is diagnosed with colorectal cancer might lower the risk of the cancer coming back and also the risk of dying from it. It is not clear, though ,if this benefit is seen in all people with colorectal cancer.
Because aspirin can have serious or even life-threatening side effects, such as bleeding from stomach irritation or stomach ulcers, most experts recommend checking with your doctor before starting it on a regular basis as a way to lower your risk of recurrence.
Drinking alcohol has been linked with an increased risk of getting colorectal cancer, especially in men. But whether alcohol affects the risk of colorectal cancer recurrence is not as clear.
It is best not to drink alcohol. For people who do drink alcohol, they should have no more than 1 drink a day for women and no more than 2 drinks a day for men. This can help lower their risk of getting certain types of cancer (including colorectal cancer). But for people who have finished cancer treatment, the effects of alcohol on recurrence risk are largely unknown.
Because this issue is complex, it’s important to discuss it with your health care team, taking into account your risk of colorectal cancer recurrence (or getting a new colorectal cancer) and your risk of other health issues linked to alcohol use.
Research has shown that colorectal cancer survivors who smoke are more likely to die from their cancer (as well as from other causes). Aside from any effects on colorectal cancer risk, quitting smoking can clearly have many other health benefits.
If you're thinking about quitting smoking and need help, talk to your doctor, or call the American Cancer Society at 1-800-227-2345 for information and support.
If the cancer does recur at some point, your treatment options will depend on where the cancer is, what treatments you’ve had before, and your overall health. For more information on how recurrent cancer is treated, see Treatment of Colon Cancer, by Stage or Treatment of Rectal Cancer, by Stage.
For more general information on recurrence, see Understanding Recurrence.
People who’ve had colorectal cancer can still get other cancers, In fact, colorectal cancer survivors are at higher risk for getting another colorectal cancer, as well as some other types of cancer. Learn more in Second Cancers After Colorectal Cancer.
It is normal to feel depressed, anxious, or worried when colorectal cancer is a part of your life. Some people are affected more than others. But everyone can benefit from help and support from other people, whether friends and family, religious groups, support groups, professional counselors, or others.
Learning to be comfortable with your body during and after colorectal cancer treatment is a personal journey, one that is different for everyone. Some people may feel self-conscious if they have a colostomy or ileostomy as a result of treatment. Some people may have sexual problems as a result of the type of surgery they had for their cancer. Information and support can help you cope with these changes over time. Learn more in Sexuality for the Man With Cancer or Sexuality for the Woman With Cancer.
The American Cancer Society medical and editorial content team
Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.
American Cancer Society. Cancer Treatment & Survivorship Facts & Figures 2019-2021. Atlanta, Ga: American Cancer Society; 2019.
Clark JW and Sanoff HK. Adjunctive therapy for patients with resected early stage colorectal cancer: Diet, exercise, NSAIDs, and vitamin D. Goldberg RM, ed. UpToDate. Waltham, MA: UpToDate Inc. https://www.uptodate.com (Accessed on February 21, 2020.)
Haggstrom DA and Cheung WY. Approach to the long-term survivor of colorectal cancer. Nekhlyudov L, ed. UpToDate. Waltham, MA: UpToDate Inc. https://www.uptodate.com (Accessed on February 21, 2020. Updated June 18, 2019.)
Meyerhardt JA, Mangu PB, Flynn PJ, et al; American Society of Clinical Oncology. Follow-up care, surveillance protocol, and secondary prevention measures for survivors of colorectal cancer: American Society of Clinical Oncology clinical practice guideline endorsement. J Clin Oncol. 2013;31(35):4465-70. doi: 10.1200/JCO.2013.50.7442. Epub 2013 Nov 12.
National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Colon Cancer. V.1.2020. Accessed at https://www.nccn.org/professionals/physician_gls/pdf/colon.pdf on Feb 21, 2020.
National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology: Rectal Cancer. V.1.2020. Accessed at https://www.nccn.org/professionals/physician_gls/pdf/rectal.pdf on Feb 21, 2020.
Rock CL, Thomson CA, Sullivan KR, et al. American Cancer Society nutrition and physical activity guideline for cancer survivors. CA Cancer J Clin. 2022. Accessed at https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/caac.21719 on March 16, 2022.
Rock CL, Thomson C, Gansler T, et al. American Cancer Society guideline for diet and physical activity for cancer prevention. CA Cancer J Clin. 2020;70(4). doi:10.3322/caac.21591. Accessed at https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21591 on June 9, 2020.
Last Revised: March 16, 2022
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