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Our highly trained specialists are available 24/7 via phone and on weekdays can assist through online chat. We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
For most men with testicular cancer, treatment can remove or destroy the cancer. The end of treatment can be both stressful and exciting. You may be relieved to finish treatment, yet it’s hard not to worry about cancer coming back. These feelings are very common if you’ve had cancer. Life after cancer means returning to some familiar things and making some new choices.
After you've completed treatment, your doctors will still want to watch you closely. Follow-up care is extremely important after treatment of testicular cancer because, even if it comes back, it’s still often curable. This is why finding it early is so important.
During these visits, your doctors will examine you and ask questions about any problems you're having. Lab tests and/or imaging tests (such as chest x-rays and CT scans) will be done to look for signs of cancer or treatment side effects. As time goes on, these visits and tests will be done less often.
Your health care team will explain what tests you need and how often they should be done. If you had a non-seminoma, follow-up testing will include blood tests of tumor markers, such as alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and lactate dehydrogenase (LDH).
Radiation treatment and some of the chemo drugs commonly used for testicular cancer have side effects. Some may last for a few weeks to months, but others can last the rest of your life. Talk to your doctor about long-term side effects you should watch for. This is also the time for you to talk to your cancer care team about any changes or problems you notice and any questions or concerns you have.
For people with non-seminoma and advanced seminoma, it is important that follow-up care includes testing of tumor marker levels. Increases in the tumor marker levels are often the first sign that the cancer has returned. The American Society of Clinical Oncology (ASCO) recommends the following schedule for testing tumor marker levels:
Alpha-fetoprotein (AFP) and beta human chorionic gonadotropin (beta-hCG) should be measured at regular times. ASCO recommends the following schedule:
ASCO recommends only checking tumor marker levels for advanced seminoma using the following schedule:
However, even after this specific follow-up period ends, people should let any doctor treating them know that they have a history of testicular cancer. This includes your primary care provider (PCP), who can then monitor for possible long-term side effects throughout your lifetime.
Make a special effort to keep all appointments with your cancer care team and follow their instructions carefully. Report any new or recurring symptoms to your doctor right away. Most of the time, if the cancer comes back, it does so in the first 2 years. Still, there's always an outside chance the cancer can come back later. There’s also a small chance that you'll develop a new cancer in the other testicle, so report any changes in your remaining testicle to your doctor.
Talk with your doctor about developing a survivorship care plan for you. This plan might include:
Even after treatment, it’s very important to keep health insurance. Tests and doctor visits cost a lot, and even though no one wants to think of their cancer coming back, this could happen.
At some point after your cancer treatment, you might find yourself seeing a new doctor who doesn’t know about your medical history. It’s important to keep copies of your medical records to give your new doctor the details of your diagnosis and treatment. Learn more in Keeping Copies of Important Medical Records.
If you have (or have had) testicular cancer, you probably want to know if there are things you can do that might lower your risk of the cancer growing or coming back, such as exercising, eating a certain type of diet, or taking nutritional supplements. Unfortunately, it’s not yet clear if there are things you can do that will help.
Adopting healthy behaviors such as not smoking, eating well, getting regular physical activity, and staying at a healthy weight might help, but no one knows for sure. However, we do know that these types of changes can have positive effects on your health that can extend beyond your risk of testicular cancer or other cancers.
So far, no dietary supplements (including vitamins, minerals, and herbal products) have been shown to clearly help lower the risk of neuroblastoma progressing or coming back. This does not mean that there are no supplements that can help, but it is important to know that none have been proven to do so.
To learn more, see Are Dietary Supplements Safe?
If the cancer does recur at some point, your treatment options will depend on where the cancer is located, what treatments you’ve had before, and your health. For more information on how recurrent cancer is treated, see Treatment Options for Testicular Cancer, by Type and Stage.
For more general information on recurrence, you may also want to see Understanding Recurrence.
Men who’ve had testicular cancer can still get other cancers. In fact, testicular cancer survivors are at higher risk for getting some other types of cancer. Learn more in Second Cancers After Testicular Cancer.
Some amount of feeling depressed, anxious, or worried is normal when cancer is a part of your life. Some people are affected more than others. But everyone can benefit from help and support from other people, whether friends and family, religious groups, support groups, professional counselors, or others. Learn more in Life After Cancer.
Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).
National Comprehensive Cancer network. NCCN Clinical Guidelines in Oncology (NCCN Guidelines). Testicular Cancer. Version 1.2025 – Jan 17, 2025. Accessed at https://www.nccn.org on Feb 18, 2025.
National Cancer Institute. Testicular Cancer Treatment (PDQ®)–Patient Version. May 17, 2023. Accessed at www.cancer.gov/types/testicular/patient/testicular-treatment-pdq on June 1, 2025.
Last Revised: August 10, 2025
American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.
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