Paget Disease of the Nipple
Paget disease of the nipple is a rare type of breast cancer involving the skin of the nipple. Paget disease starts in the breast ducts and spreads to the skin of the nipple and then to the areola, the dark circle around the nipple. Paget disease usually affects only one nipple. It’s almost always linked to either ductal carcinoma in situ (DCIS) or infiltrating ductal carcinoma.
What are the signs and symptoms of Paget disease of the nipple?
The skin of the nipple and areola often looks crusted, scaly, and red. There may be blood or yellow fluid coming out of the nipple. Sometimes the nipple looks flat. It also might burn or itch.
How is Paget disease of the nipple diagnosed?
Most people with Paget disease of the nipple also have tumors in the same breast. One or more of the following imaging tests may be done to check for other breast changes:
Paget disease of the nipple is diagnosed by a biopsy, removing a small piece of the breast tissue and looking at it under a microscope. In some cases, the entire nipple may be removed. Only a biopsy can tell for sure that cancer is present.
How is Paget disease of the nipple treated?
Paget disease is often treated by removing the entire breast (mastectomy). Breast-conserving surgery followed by whole-breast radiation therapy is another option for some women who do not have tumors in the breast.
If no lump is felt in the breast tissue, and your biopsy results show the cancer has not spread, the outlook (prognosis) is excellent.