PDFs by language
Our 24/7 cancer helpline provides support for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.
Chat live online
Select the Live Chat button at the bottom of the page
At our National Cancer Information Center trained Cancer Information Specialists can answer questions 24 hours a day, every day of the year to empower you with accurate, up-to-date information to help you make educated health decisions. We connect patients, caregivers, and family members with valuable services and resources.
Or ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
Grantee: Kosj Yamoah, MD, PhD
Institution: H. Lee Moffitt Cancer Care & Research Institute in Tampa, Fla.
Term: 7/1/2017 to 6/30/2022
The Challenge: African American men in the United States are 1.7 times more likely to get prostate cancer and 2.3 times more likely to die from it compared to European American men. Doctors use a tool to help predict how aggressive a man’s prostate cancer may be. With this information, the doctor can better guide decisions about treatment. The problem is, it’s not clear whether these tools apply to African American men.
The Research: Previous researchers have established that ethnic differences in genes affect prostate tumors. These genetic differences are partly responsible for the increased risk an African American man has for getting prostate cancer and dying from it. Yamoah and his fellow researchers believe that genetic information in a prostate tumor may give hints about where the tumors are located, making them easier to find and biopsy. The team also thinks tumor genes may suggest how aggressively the cancer will spread to other parts of the body.
With the support of a grant from the American Cancer Society, Yamoah is developing a new predictive tool, using genetic information, to help guide treatment for prostate cancer. Relying on genetic data means the tool should be valuable to African American men as well as European American men.
The Goal and Long-term Possibilities: Yamoah’s findings may improve doctors’ ability to find and diagnose prostate tumors and recommend more personalized treatment choices for aggressive tumors. His work to better use genetic differences between ethnic groups may help reduce the large differences (disparities) for getting and dying from prostate cancer between ethnic groups. To learn more, listen to this podcast with Dr. Yamoah.