How Surgery Is Used for Cancer
Surgery is used to prevent, diagnose, stage, and treat cancer. Surgery can also relieve (palliate) discomfort or problems related to cancer. Sometimes, one surgery can take care of more than one of these goals. In other cases, different operations may be needed over time. You will find specific cancer operations discussed in treatment information for each cancer type.
Surgery to diagnose cancer
Surgery is one way to help diagnose cancer. In most cases, the only way to know if a person has cancer and what kind of cancer it is, is by taking out a small piece of tissue (called a sample) and testing it. The diagnosis is made by looking at cells from the sample with a microscope or by doing other lab tests on it.
This procedure is called a biopsy. Biopsies taken during surgery are often referred to as surgical biopsies.
How a sample is taken depends on where the tumor is and what type of cancer is suspected. For example, the method used for prostate biopsies is different from those used for lung biopsies.
Learn more about different types of biopsies in Testing Biopsy and Cytology Specimens for Cancer.
Surgery to stage cancer
Staging surgery is done to find out how much cancer there is and how far it has spread. During this surgery, the area around the cancer including lymph nodes and nearby organs is examined. This is important because it provides information to guide treatment decisions and predict how people will respond to treatment. To learn more about this, see our information on Cancer Staging.
Curative or primary surgery is usually done when cancer is found in only one part of the body, and it’s likely that all of the cancer can be removed. In this case, surgery can be the main treatment. It may be used alone or along with other treatments like chemotherapy or radiation therapy, which can be given before or after the operation.
Surgery to debulk cancer
Debulking surgery is used to remove some, but not all, of the cancer. It’s sometimes done when taking out the entire tumor would cause too much damage to nearby organs or tissues. For example, it may be used for advanced cancer of the ovary and some lymphomas. In these cases, the doctor may take out as much of the tumor as possible and then treat what’s left with radiation, chemotherapy, or other treatments.
This type of surgery is used to treat problems caused by advanced cancer. Palliative surgery can be used to correct a problem that’s causing discomfort or disability. For example, some cancers in the belly (abdomen) may grow large enough to block off (obstruct) the intestine. If this happens, surgery can be used to remove the blockage. Palliative surgery may also be used to treat pain when the pain is hard to control by other means. Palliative surgery helps ease problems caused by cancer and helps people feel better, but it’s not done to treat or cure the cancer itself.
Supportive surgery is done to help make it easier for people to get other types of treatment. For example, a vascular access device such as a Port-A-Cath® or Infusaport® is a thin, flexible tube that can be surgically placed into a large vein and connected to a small drum-like device that’s placed just under the skin. A needle is put into the drum of the port to give treatments and draw blood, instead of putting needles in the hands and arms each time.
Restorative (reconstructive) surgery
Reconstructive surgery is used to improve the way a person looks after major cancer surgery. It’s also used to restore the function of an organ or body part after surgery. Examples include breast reconstruction after mastectomy or the use of tissue flaps, bone grafts, or prosthetic (metal or plastic) materials after surgery for head and neck cancers. For more on these types of reconstructive surgery, see Breast Reconstruction Surgery and Oral Cavity and Oropharyngeal Cancer.
Preventive (prophylactic) surgery
Preventive or prophylactic surgery is done to remove body tissue that’s likely to become cancer – even though there are no signs of cancer at the time of the surgery.
Sometimes an entire organ is removed when a person has a condition that puts them at very high risk for having cancer there. The surgery is done to reduce cancer risk and help prevent the chance of cancer, but it doesn’t guarantee cancer prevention.
For example, some women with a strong family history of breast cancer have an inherited change in a breast cancer gene (called BRCA1 or BRCA2). Because the risk of breast cancer is very high, removing the breasts (prophylactic mastectomy) may be considered. This means the breasts are removed before cancer is found.
Hosoya Y, Lefor AT. Surgical Oncology: Laparoscopic Surgery. In: DeVita VT, Lawrence TS, Rosenberg SA, eds. Cancer Principles & Practice of Oncology. 9th Ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2011:277-288.
Lee SJ, Ito Y, Phillips EH. Minimally Invasive Surgery for Cancer. In: Silberman H, Silberman AW, eds. Principles and Practice of Surgical Oncology. Philadelphia, Pa: Lippincott Williams & Wilkins; 2010:200-210.
National Cancer Institute. Cryosurgery in Cancer Treatment: Questions and Answers. Accessed at www.cancer.gov/cancertopics/factsheet/Therapy/cryosurgery on March 8, 2016.
National Cancer Institute. Lasers in Cancer Treatment. Accessed at www.cancer.gov/cancertopics/factsheet/Therapy/lasers on March 8, 2016.
Niederhuber JE. Surgical Interventions in Cancer. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff's Clinical Oncology. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2014:372-380
Last Medical Review: April 12, 2016 Last Revised: April 19, 2016