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For many years, rumors have circulated online suggesting that underarm antiperspirants might cause breast cancer. While the research on this topic is limited, most studies have not found a link between antiperspirant use and the development of breast cancer.
There are no strong epidemiologic studies (studies in people) that link breast cancer risk and antiperspirant use, and very little scientific evidence to support this claim.
The studies in people that have looked at this issue have been case-control studies, in which people with and without breast cancer have been asked about previous antiperspirant use. These types of studies can often be hard to interpret because they typically rely on a person’s memory of antiperspirant use many years earlier, and people with cancer tend to be more likely to recall exposures they think might be linked to their cancer.
Still, most case-control studies looking at antiperspirant use and breast cancer risk have not found a link between them. This includes a large, carefully designed study comparing about 800 women with breast cancer and a similar number of women without the disease. This study found no link between breast cancer risk and antiperspirant use, deodorant use, or underarm shaving.
A couple of studies have suggested a possible relationship, but the results of these studies need to be interpreted with caution because of their small size, and because the way they were designed limits the conclusions that can be drawn from them. Larger, better-designed epidemiologic studies would be needed to support these results.
There is no established evidence of this. Razor nicks may increase the risk of skin infection. If the underarm skin is already broken or infected, it is possible that some antiperspirants could cause slight irritation. But it is unlikely that this is a major source of carcinogens (cancer-causing substances) that get into the body and reach the breast cells.
There is no current epidemiological evidence that parabens increase breast cancer risk.
Parabens are chemicals used as preservatives and as food additives. They can be found in many types of make-up (like lipstick, mascara, concealer, and foundation) and skin care products (like lotion, shaving products, and sunscreen). Parabens can be absorbed through the skin.
Parabens have been raised as a possible health concern because lab studies have shown that they have weak estrogen-like properties. Estrogen is a female hormone known to cause breast cells (both normal and cancer cells) to grow. And some conditions that increase the body's exposure to estrogen (like not having children, late menopause, obesity, etc.) have been linked to an increased risk of breast cancer.
While some forms of parabens have been found in the urine in up to 99% of people in the US, so far, studies in people have not shown any direct link between parabens and any health problems, including breast cancer. There are also many other compounds in the environment that mimic naturally produced estrogen.
Although there are no clear health risks from parabens in food, drugs, cosmetics, and skin care products, people concerned about being exposed to parabens might choose to avoid products containing them. Consumer products containing parabens are required to list them as ingredients. Most parabens have names containing the word “paraben,” making them easy to find.
According to the US Food and Drug Administration (FDA),many major brands of antiperspirants and deodorants do not currently contain parabens, although some might.
Aluminum-based compounds are the active ingredients in antiperspirants. They block the sweat glands to keep sweat from getting to the skin's surface. Some researchers have theorized that these aluminum compounds might be absorbed by the skin and cause changes in estrogen receptors of breast cells. Because estrogen can promote the growth of both cancer and non-cancer breast cells, some scientists have suggested that using the aluminum-based compounds in antiperspirants may be a risk factor for the development of breast cancer.
But it isn’t clear that much aluminum is absorbed through the skin. One study that looked at the absorption of aluminum from antiperspirants containing aluminum chlorohydrate applied to the underarms found that only a tiny fraction (0.012%) was absorbed. The actual amount of aluminum absorbed would be much less than what would be expected to be absorbed from the foods a person eats during the same time.
It also doesn’t seem that breast cancer tissue contains more aluminum than normal breast tissue. A study that looked at women with breast cancer found no real difference in the concentration of aluminum between the cancer and the surrounding normal tissue.
At this point, there is no clear link between antiperspirants containing aluminum and breast cancer.
The lymph nodes in our bodies help clear out bacteria, viruses, and other possible threats, but the lymph nodes do not release waste or toxins through sweating. In fact, lymph nodes are not connected to sweat glands. Sweat glands are located in the skin, not in the lymph nodes. The main function of sweat glands is to help cool the body, not to get rid of toxins.
Most cancer-causing substances that enter the body are removed from the blood by the kidneys and by the liver. Substances removed by the kidneys are released into urine, while those taken by the liver are released into bile. The bile then mixes with and is eliminated with feces.
Lymph nodes can be found throughout the breasts and have an important role. The underarm (axillary) nodes filter most of the liquid lymph flowing out of the breast before it goes back into the body's bloodstream. These nodes are under the arm, in the upper outer quadrant of the breast, and near the collarbone.
The breast quadrants are not actually all the same size. About half of all breast cancers develop in the upper outer part of the breast, but this is most likely because there is more breast tissue in this area. The number of breast cancers in the upper outer part of the breast is in proportion to the amount of breast tissue in that area.
There is no evidence to suggest that the location of cancers within the breast is related to using antiperspirants or underarm shaving.
Men are much less likely than women to develop breast cancer, but this is mostly because men have much less breast tissue than women.
Hormones also play a role. Men with metabolic or genetic conditions that lead to increased estrogen levels have an increased risk of developing breast cancer.
Underarm hair and antiperspirant absorption have not been linked to male breast cancer risk.
You are likely to be advised not to use antiperspirant or deodorant on the day you get a mammogram (an x-ray of the breast) because many of these products contain aluminum. This metal can show up on mammograms as tiny white specks. These specks can look like microcalcifications, which are one of the things doctors look for as a possible sign of breast cancer. Not using these products helps prevent any confusion when the mammogram films are reviewed.
Women concerned about breast cancer can learn about risk factors for breast cancer and possible ways to reduce breast cancer risk in Breast Cancer Risk and Prevention.
The American Cancer Society has information about all aspects of breast cancer, including causes, prevention, early detection, diagnosis, and treatment. Contact us at 1-800-227-2345.
You can also talk to your doctor, nurse, or other health care providers.
The American Cancer Society medical and editorial content team
Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.
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National Cancer Institute Fact Sheets. Antiperspirants/Deodorants and Breast Cancer. 2016. Accessed at https://www.cancer.gov/about-cancer/causes-prevention/risk/myths/antiperspirants-fact-sheet on October 10, 2022.
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US Centers for Disease Control and Prevention. Parabens Factsheet. 2017. Accessed at https://www.cdc.gov/biomonitoring/Parabens_FactSheet.html on October 10, 2022.
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US Food and Drug Administration. Parabens in Cosmetics. 2022. Accessed at https://www.fda.gov/cosmetics/cosmetic-ingredients/parabens-cosmetics on October 10, 2022.
Last Revised: October 19, 2022
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